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Isoescin IB
CAS No. 219944-46-4
Isoescin IB( —— )
Catalog No. M21793 CAS No. 219944-46-4
Isoescin IB, isolated from horse chestnut tree seeds, is an isomer of Escin IB.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 252 | In Stock |
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| 10MG | 374 | In Stock |
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| 25MG | 619 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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Biological Information
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Product NameIsoescin IB
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NoteResearch use only, not for human use.
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Brief DescriptionIsoescin IB, isolated from horse chestnut tree seeds, is an isomer of Escin IB.
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DescriptionIsoescin IB, isolated from horse chestnut tree seeds, is an isomer of Escin IB. Isoescin IB and Escin IB are the chief active ingredients in escin.
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In Vitroβ-Escin (mainly consisting of escin Ia and escin Ib) is the major active ingredient in horse chestnut seeds extracts. β-escin can inhibit proliferation and/or induce apoptosis in various types of cancer cells including A549 cell, HT-29 cell, HCC cell, OVCAR3 cell and H-Ras 5RP7 cell. β-escin may be useful as a chemopreventive agent, especially for tumors associated with an inflammatory response. As the minor component of escin, α-escin (mainly consisting of isoescin Ia and isoescin Ib) exhibits lower bioactivity.
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In Vivo——
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Synonyms——
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PathwayNatural Products
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TargetTerpenoids
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number219944-46-4
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Formula Weight1131.26
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Molecular FormulaC??H??O??
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (88.40 mM)
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SMILESCC(OC[C@]1([C@H]2O)[C@](CC(C)(C)[C@H]2OC(/C(C)=C\C)=O)([H])C3=CC[C@@]4([H])[C@@](C)(CC[C@]5([H])[C@@]4(CC[C@H](O[C@@](O[C@H](C(O)=O)[C@@H](O[C@]([C@@H]([C@@H](O)[C@@H]6O)O)([H])O[C@@H]6CO)[C@@H]7O)([H])[C@@H]7O[C@]([C@@H]([C@@H](O)[C@@H]8O)O)([H])O[C@@H]8CO)[C@]5(C)CO)C)[C@]3(C)C[C@H]1O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wu XJ, et al. Comparative pharmacokinetics and the bioavailability of escin Ib and isoescin Ib following the administration of escin, pure escin Ib and isoescin Ib in rats.J Ethnopharmacol. 2014 Feb 3;151(2):839-45.
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Escin IB
Escin IB is a saponin isolated from skin and the endosperm of seeds of horse chestnut (Aesculus hippocastanum). Escin IB shows inhibitory effect on pancreatic lipase activity.
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Isoescin IB
Isoescin IB, isolated from horse chestnut tree seeds, is an isomer of Escin IB.
